Lab Members

Contact

Institute of Molecular & Cellular Anatomy, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm
M24/Room 4307

Research interest

Our research group focuses on investigating the molecular mechanisms that direct brainstem development and control of bodily homeostasis. 

CV 

2018-2025
Charité Universitätsmedizin, Berlin, Germany, Principal Investigator.

2010-2018
Max-Delbrück-Centrum, Berlin, Germany, Postdoctoral Fellow

2007-2010
University College London, London United Kingdom, Ph.D. in Neuroscience

Memberships

Society for Neuroscience (USA)

American Association for the Advancement of Science (USA)

Neurowissenschaftliche Gesellschaft (Germany)

Anatomische Gesellschaft (Germany)

Third-Party Funding

2024    Congenital Central Hypoventilation Syndrome Network (# 18-2024) .

2023    Deutsche Forschungsgemeinschaft (project # 514060831).

2022    Deutsche Forschungsgemeinschaft (project # 512746157).

2021    Deutsche Forschungsgemeinschaft (project # 450241946).

2020    Fritz-Thyssen-Stiftung (grant # 10.20.1.004M).

Awards

2016             Award from the Max-Delbrück-Centrum for excellence in Research.

2012-2014   Marie Curie Fellowship, European Commission (# 302477).

2007-2010   Ph.D. Fellowship from the Mexican Council for Science (# 1896887).

2007-2010   Ph.D. graduate fellowship from University College London.

2008-2009   Fellowship from University College London Alumni Scholarship program.

2004-2006   M.Sc. fellowship from National Autonomous University of Mexico.

2004-2006   M.Sc. fellowship from the Mexican Council for Science.

2003            B.Sc. undergraduate fellowship from the Mexican Council for Science.

Publications (selected)

Cui K., Xia Y., Patnaik A., Salivara A., Lowenstein E.D., Isik E.G., Knorz A.L., Airaghi L., Crotti M., Garratt A.N., Meng F., Schmitz D., Studer M., Rijli F.M., Nothwang H.G., Rost B.R., Strauß U., Hernandez-Miranda L.R. (2024) Genetic identification of medullary neurons underlying congenital hypoventilation. Science Advances 10: eadj0720.  

Lowenstein E.D., Rusanova A., Stelzer J, Hernaiz-Llorens M, Schroer A E., Epifanova E., Isik E.G., Buchert S., Jia S., Tarabykin V., Hernandez-Miranda L.R. (2021) Olig3 regulates early cerebellar development. eLife 10:e64684.

Hernandez-Miranda L.R., Ibrahim D., Ruffault P.L., Larrosa M., Balueva K., Müller T., van de Weerd W., Stolte-Dijkstra I., Hostra R.M.W., Brunet J.F., Fortin G., Mundlos S., Birchmeier C. (2018) Mutation in LBX1/Lbx1 precludes transcription factor cooperativity and causes congenital hypoventilation in humans and mice. Proceedings of the National Academy of Sciences of the United States of America (PNAS) 115: 13021-13026.

Hernandez-Miranda L.R., Ruffault P.L., Bouvier J., Murray A., Morin-Surun M.P., Zampieri N., Cholewa-Waclaw J.B., Ey E., Brunet J.F., Champagnat J., Fortin G., Birchmeier C. (2017). Genetic identification of a hindbrain nucleus essential for innate vocalization. Proceedings of the National Academy of Sciences of the United States of America (PNAS) 114:8095-8100.

Piwecka M.*,Glažar P.*,Hernandez-Miranda L.R.*, Memczak S., Wolf S.A., Rybak-Wolf A., Filipchyk A., Klironomos F., Cerda Jara C.A., Fenske P., Trimbuch T., Zywitza V., Plass M., Schreyer L., Ayoub S., Kocks C., Kühn R., Rosenmund C., Birchmeier C., Rajewsky N. (2017) Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function. Science 357 (6357):eaam8526. (*co-first authors).